Know Your Treatment
Treatment options to lower LDL
- Healthy diet: A diet low in saturated fat (7 percent of total calories or less), low in cholesterol (200 mg or less daily), and high in fiber can lower LDL cholesterol. A cholesterol-lowering diet can reduce LDL by up to 30 percent.
- Medications: Consult with your physician first.
- Statins block the production of cholesterol in the liver, lower LDL and triglycerides.
- PCSK9 inhibitors are an exciting new class of medicines which dramatically lower cholesterol when statin therapy is not enough to reaching target goals, is not tolerated or is ineffective. They are monoclonal antibodies given by injection every two-to-four weeks. They work by preventing breakdown of the LDL -- receptors on the cell surface which bind cholesterol and facilitate its disposal. Potentially harmful cholesterol molecules are markedly decreased by significantly improving the number of these receptors. This class of drugs is indicated to reduce risk of developing cardiovascular events in people with very high risk, particularly those who already have a documented disease and continue to have events despite appropriate lipid-modifying therapy and those with a genetic condition of very high cholesterol called familial hypercholesterolemia.
- Cholesterol absorption inhibitors prevent the absorption of cholesterol from the small intestines into the blood.
- Resins work in the intestines to deplete the body's supply of cholesterol.
- Fibrates reduce the production of triglycerides and can increase HDL cholesterol.
- Nicotinic Acid (niacin) is a B-complex vitamin found in food, but also available in high doses by prescription. It lowers LDL and raises HDL.
- Some people with high cholesterol, other cholesterol problems, or some other medical conditions achieve the best results with combination drugs – pills that contain more than one medication.
- Regular aerobic exercise can both lower bad cholesterol (LDL) and increase good cholesterol (HDL).